Had a great seminar yesterday by a colleague from the genetics department. He gave an intro/overview on Tajima's D (basically a statistics test to check whether a given stretch of DNA is evolving neutrally or under some non-random form, e.g. by selection). One thing he showed was Tajima's D over all human Chromosomes (which can be loaded as a track in the UCSC Genome browser) and that made me think if this is not telling us that large parts of the genome simply can't be functional in the way the ENCODE press hype implied. Okay, it's agreed now, that the 80% are purely for the press, but even if it was less.
So is it? Tajima's D : ENCODE media hype
1 : 0
Wouldn't the Tajima's D value indicate much more regions selected upon? Or is the sliding window they used to large? Or am I thinking this wrong? Very happy for discussion. Actually very happy for explanations...
Zen of the day: Constant turning of pebbles is needed to find the truth. Ever so often it's pebbles in your own head. Kazing!!!
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